The announcement follows recent skirmishes with rival India over disputed Kashmir during which Pakistan said it shot down two Indian planes and captured a pilot, who was later returned to India, AP reported.
An air force statement says a JF-17 multi-role fighter aircraft on Tuesday fired the new missile, which has "day-and-night capability to engage a variety of targets with pinpoint accuracy."
A "smart" weapon is typically military language for a guided missile.
Air Force chief Mujahid Anwar was quoted as saying that "Pakistan is a peace-loving nation but if subjected to aggression by adversary, we will respond with full force."
There was no further information on the type of missile fired.
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