Avichai Mandelblit is expected to announce his decision on Thursday, after more than two years of intense investigations and deliberations, AP reported.
An indictment would mark the first time that a sitting prime minister has been charged.
Police have recommended indicting Netanyahu for bribery, fraud and breach of trust in three different cases. Mandelblit is expected to inform Netanyahu's lawyers he intends to press charges pending a final hearing for the suspect.
Netanyahu denies any wrongdoing and calls the allegations a media-orchestrated witch hunt aimed at removing him from office. He has vowed to carry on and is deadlocked in the polls ahead of the April 9 elections.
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